Protein  Disulphide  Linkage Modeler

The Protein Disulphide Linkage Modeler is a software tool for the rapid analysis of mass spectromic disulphide cross-link mapping experiments. The tool can be used to determine disulphide linkages in proteins that have either been completely or partially digested with enzymes. The masses of all possible disulphide-linked multi-chain peptide combinations are calculated from the known protein sequence and compared to the experimentally determined masses of disulphide-linked multi-chain peptides.

The Protein Disulphide Linkage Modeler is available for download if you wish to run it on your own system or it can be run from the Manitoba Centre for Proteomics server. Click on the links above to either download or run the public version.

NOTE: The download package includes the files needed to set up a web site which allows users to run DisulphideModeler via a web browser. The executable program can run from either Windows or Linux, but in order for the formatted XML display to render correctly, the browser must be Internet Explorer 6.